rare

POEMS syndrome

POEMS is a rare paraneoplastic syndrome caused by a clone of aberrant cells. The name POEMS is an acronym for some of the disease's major signs and symptoms, as is PEP.

Underlined words are explained — tap any of them.

Symptoms — what it feels like

·Papilledema, polyneuropathy, edema, hyperpigmentation, hypogonadism, visceromegaly, amenorrhea, gynecomastia, erectile , and testicular .

Causes — why it happens

·<!-- or

How it's found

· Criteria.

Treatment

·, low-dose alkylators, blood stem cell , high-dose .

Complications

·Multiorgan failure, restrictive lung disease, , cardiorespiratory failure, progressive inanition, , capillary leak-like , and renal failure.

Outlook

·Median survival of 13.8 years.

More in Thyroid & Hormones

Hypothyroidism Hyperthyroidism Goitre Hashimoto's thyroiditis Graves' disease Thyroid cancer Cushing's syndrome Addison's disease Acromegaly Hyperparathyroidism Diabetes insipidus Pheochromocytoma

See all of Thyroid & Hormones →

Plain-language summary adapted from Wikipedia. Not medical advice.