D2I2.
genetic

Laron syndrome

Laron (LS), also known as growth insensitivity or growth hormone (GHRD), is an disorder characterized by a lack of -like growth factor 1 production in response to growth hormone. It is usually caused by inherited growth hormone receptor (GHR) . The syndrome is named after the scientist Zvi Laron who first discovered the syndrome in 1966.

Underlined words are explained — tap any of them.

Symptoms — what it feels like

  • ·Short , truncal , facial dysmorphism

Causes — why it happens

  • · growth gene ( 5)

Treatment

  • ·IGF-1, Mecasermin
Plain-language summary adapted from Wikipedia. Not medical advice.