D2I2.
genetic⚑ High burden in India

Congenital adrenal hyperplasia

adrenal hyperplasia (CAH) is a group of disorders characterized by impaired cortisol synthesis. It results from the of one of the five enzymes required for the synthesis of cortisol in the adrenal cortex. Most of these disorders involve excessive or deficient production of hormones such as glucocorticoids, mineralocorticoids, or sex , and can alter development of primary or secondary sex characteristics in some affected infants, children, or adults. It is one of the most common autosomal recessive disorders in humans.

Underlined words are explained — tap any of them.

Symptoms — what it feels like

  • ·Excessive urination of sodium, virilism, early, delayed, or absent puberty, hyperandrogenism

Causes — why it happens

  • · in genes responsible for the production of enzymes required for the synthesis of cortisol in the adrenal cortex

Treatment

  • ·-->
Plain-language summary adapted from Wikipedia. Not medical advice.