D2I2.
common

Sertoli cell-only syndrome

Sertoli cell-only (SCOS), also known as germ cell aplasia, is defined by azoospermia where the testicular seminiferous tubules are lined solely with Sertoli cells. Sertoli cells contribute to the formation of the blood-testis barrier and aid in sperm generation. These cells respond to follicle-stimulating , which is secreted by the hypothalamus and aids in spermatogenesis.

Underlined words are explained — tap any of them.

Symptoms — what it feels like

  • ·, azoospermia, testicular , high FSH levels.

Causes — why it happens

  • ·Y- microdeletions, chemical or toxin exposure, therapy, or severe testicular injuries.

How it's found

  • ·Testicular .

Treatment

  • ·Microscopic testicular sperm extraction or testicular sperm .
Plain-language summary adapted from Wikipedia. Not medical advice.