D2I2.
acute

Serotonin syndrome

Serotonin (SS) consists of a group of symptoms that may occur with the use of certain serotonergic medications or drugs. The symptoms can range from mild to severe, and are potentially fatal. Symptoms in mild cases include high blood pressure and a fast heart rate, usually without a fever. Symptoms in moderate cases include high body temperature, agitation, overactive reflexes, tremor, sweating, pupils, and . In severe cases, body temperature can increase to greater than 41.1 °C (106.0 °F). may include and extensive muscle breakdown.

Underlined words are explained — tap any of them.

Symptoms — what it feels like

  • ·High body temperature, agitation, increased reflexes, tremors, sweating, pupils,

Causes — why it happens

  • ·Selective serotonin reuptake inhibitor (SSRI), serotonin norepinephrine reuptake inhibitor (SNRI), monoamine oxidase inhibitor (MAOI), tricyclic (TCAs), amphetamine, methylene blue, pethidine (meperidine), tramadol, dextromethorphan, ondansetron, cocaine

How it's found

  • ·Based on symptoms and medication use

Treatment

  • ·Active cooling
Plain-language summary adapted from Wikipedia. Not medical advice.