D2I2.
neurodegenerative

Multiple system atrophy

Multiple system (MSA) is a rare disorder characterized by tremors, slow movement, muscle rigidity, postural instability, autonomic and ataxia. This is caused by progressive of neurons in several parts of the brain including the basal ganglia, inferior olivary nucleus, and cerebellum. MSA was first described in 1960 by Milton Shy and Glen Drager and is also known as Shy–Drager .

Underlined words are explained — tap any of them.

Symptoms — what it feels like

  • ·Parkinsonism, xerostomia, dysautonomia, ataxia

Causes — why it happens

  • ·Unknown

How it's found

  • ·MRI, CT scan, autopsy

Treatment

  • ·Physical therapy, hospice care

Complications

  • · , ,

Outlook

  • ·Life expectancy 6–12 years after onset of symptoms
Plain-language summary adapted from Wikipedia. Not medical advice.