genetic

Hunter syndrome

Hunter , or type II, is a rare inherited storage disease in which large sugar molecules called build up in body . Hunter syndrome is caused by a of the lysosomal iduronate-2-sulfatase (I2S). The lack of this enzyme causes heparan sulfate and dermatan sulfate to in all body tissues. Hunter syndrome is the only MPS syndrome to exhibit inheritance.

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Symptoms — what it feels like

· abnormalities, hearing loss, , enlarged liver and

Causes — why it happens

·Defiency of the iduronate-2-sulfatase

Complications

·Upper disease; failure

Outlook

·In severe cases, death usually occurs by age 15. In attenuated cases, patients may survive into their 50s

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Plain-language summary adapted from Wikipedia. Not medical advice.