D2I2.
autoimmune

Guillain–Barré syndrome

Guillain–Barré (GBS) is a rapid-onset muscle weakness caused by the system damaging the nervous system. Typically, both sides of the body are involved, and the initial symptoms are changes in sensation or pain often in the back along with muscle weakness, beginning in the feet and hands, often spreading to the arms and upper body. The symptoms may develop over hours to a few weeks. During the acute phase, the disorder can be life-threatening, with about 15% of people developing muscle weakness requiring mechanical . Some are affected by changes in the function of the autonomic nervous system, which can lead to dangerous abnormalities in heart rate and blood pressure.

Underlined words are explained — tap any of them.

Symptoms — what it feels like

  • ·Muscle weakness beginning in the feet and hands, usually ascending

Causes — why it happens

  • ·Typically triggered by an ; occasionally by

How it's found

  • ·Based on symptoms, nerve conduction studies, lumbar puncture

Treatment

  • ·Supportive care, , plasmapheresis

Complications

  • ·Breathing difficulties, heart and blood pressure problems

Outlook

  • ·Weeks to years for recovery
Plain-language summary adapted from Wikipedia. Not medical advice.