D2I2.
common

Achlorhydria

Achlorhydria and hypochlorhydria are states where the production of hydrochloric acid in secretions of the stomach is absent or low, respectively. Achlorhydria is commonly a complication of some other disease, such as Helicobacter pylori or pernicious , as well as a possible side effect of long-term use of proton pump .

Underlined words are explained — tap any of them.

Symptoms — what it feels like

  • ·Most of the time none, but may cause and not limited to, epigastric pain, other pain, unintentional weight loss, , , vomiting, , , early satiety

Causes — why it happens

  • ·Pernicious , helicobacter pylori , , bypass , VIPoma, PPI use, gastric cancer, (rarely) radiotherapy

Treatment

  • ·Addressing underlying cause and managing SIBO and nutrient deficiencies

Complications

  • ·Small overgrowth, nutrient deficiencies, adenocarcinoma (rare), gastric carcinoid tumor (rare)
Plain-language summary adapted from Wikipedia. Not medical advice.