D2I2.
genetic

5α-Reductase 2 deficiency

5α-Reductase 2 (5αR2D) is an condition caused by impairing the function of SRD5A2, a gene located on 2 and encoding the 5α-reductase type 2 (5αR2). 5αR2 is expressed in specific and catalyzes the transformation of testosterone (T) to 5α-dihydrotestosterone (DHT). DHT plays a key role in the process of sexual differentiation.

Underlined words are explained — tap any of them.

Causes — why it happens

  • · in the SRD5A2 gene.

Treatment

  • ·-->
Plain-language summary adapted from Wikipedia. Not medical advice.