D2I2.
neurodegenerative

Progressive supranuclear palsy

Progressive supranuclear palsy (PSP) is a late-onset disease involving the gradual deterioration and death of specific volumes of the brain, linked to 4-repeat tau pathology. The condition leads to symptoms including loss of balance, slowing of movement, difficulty moving the eyes, and impairment. PSP may be mistaken for other types of neurodegeneration such as Parkinson's disease, frontotemporal and Alzheimer's disease. It is the second most common tauopathy behind Alzheimer's disease. The cause of the condition is uncertain, but involves the accumulation of tau within the brain. Medications such as levodopa and amantadine may be useful in some cases.

Underlined words are explained — tap any of them.

Symptoms — what it feels like

  • ·Impaired balance
  • ·slowed movements
  • ·difficulty moving eyes
  • ·

Causes — why it happens

  • ·Unknown

How it's found

  • ·corticobasal
  • ·FTDP-17
  • ·Alzheimer's disease

Prevention

  • ·physical therapy
  • ·occupational therapy

Treatment

  • ·Medication
  • ·physical therapy
  • ·occupational therapy

Outlook

  • ·Fatal (usually 7–10 years after )
Plain-language summary adapted from Wikipedia. Not medical advice.