D2I2.
autoimmune

Primary biliary cholangitis

Primary biliary cholangitis (PBC), previously known as primary biliary , is an disease of the liver. It results from a slow, progressive destruction of the small bile ducts of the liver, causing bile and other toxins to build up in the liver, a condition called cholestasis. Further slow damage to the liver can lead to scarring, , and eventually cirrhosis.

Underlined words are explained — tap any of them.

Symptoms — what it feels like

  • ·Cholestasis, pruritus,

Causes — why it happens

  • ·

How it's found

  • ·Anti-mitochondrial
  • ·Liver

Treatment

  • ·Ursodeoxycholic acid, obeticholic acid, cholestyramine

Complications

  • ·, failure, portal
Plain-language summary adapted from Wikipedia. Not medical advice.