genetic

Malignant hyperthermia

hyperthermia (MH) is a type of severe reaction that occurs in response to particular medications used during general anesthesia, among those who are susceptible. Symptoms include muscle rigidity, fever, and a fast heart rate. can include muscle breakdown and high blood . Most people who are susceptible to MH are generally unaffected when not exposed to triggering agents.

Underlined words are explained — tap any of them.

Symptoms — what it feels like

·Muscle rigidity, high body temperature, fast heart rate

Causes — why it happens

·Volatile anesthetic agents or succinylcholine in those who are susceptible

How it's found

·Based on symptoms and situation, caffeine-halothane contracture test

Prevention

·Avoiding potential triggers in those susceptible

Treatment

·Dantrolene, supportive care

Complications

·Rhabdomyolysis, high blood

Outlook

·Risk of death: 5% (treatment), 75% (no treatment)

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Plain-language summary adapted from Wikipedia. Not medical advice.