Chronic thromboembolic pulmonary hypertension
thromboembolic (CTEPH) is a long-term disease caused by a blockage in the blood that deliver blood from the heart to the lungs. These blockages cause increased resistance to flow in the pulmonary tree, which in turn leads to a rise in pressure in these . The blockages either result from organised blood clots that usually originate from the deep veins of the lower limbs of the body (thromboembolism) and lodge in the pulmonary arterial tree after passing through the right side of the heart. The blockages may also result from scar that forms at the site where the clot has damaged the endothelial lining of the pulmonary arteries, causing permanent fibrous obstruction. Most patients have a combination of microvascular and macrovascular obstruction. Some patients may present with normal or near-normal pulmonary pressures at rest despite disease. These patients are labelled as having chronic thromboembolic disease (CTED).
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How it's found
- ·Invasively measured mean pressure combined with specialist
Treatment
- · endarterectomy, Balloon pulmonary angioplasty, medical treatment