D2I2.
genetic

Cystic fibrosis

(CF) is a disorder inherited in an manner that impairs the normal clearance of from the lungs, which facilitates the colonization and of the lungs by , notably Pseudomonas aeruginosa and aureus. CF is a rare genetic disorder that affects mostly the lungs, but also the , liver, kidneys, and . The hallmark feature of CF is the accumulation of thick mucus in different organs. Long-term issues include difficulty breathing and coughing up mucus as a result of frequent lung . Other signs and symptoms may include infections, poor growth, fatty , clubbing of the fingers and toes, and in most males. Different people may have different degrees of symptoms.

Underlined words are explained — tap any of them.

Symptoms — what it feels like

  • ·Difficulty breathing, coughing up , poor growth, fatty

Causes — why it happens

  • · ( )

How it's found

  • ·Sweat test, testing

Treatment

  • ·Physiotherapy, , replacement, transmembrane conductance regulator modulators, lung

Outlook

  • ·Life expectancy between 42 and 50 years (developed world)
Plain-language summary adapted from Wikipedia. Not medical advice.