D2I2.
genetic

Cystic fibrosis

(CF) is a disorder inherited in an manner that impairs the normal clearance of mucus from the lungs, which facilitates the colonization and of the lungs by , notably Pseudomonas aeruginosa and Staphylococcus aureus. CF is a rare genetic disorder that affects mostly the lungs, but also the , liver, kidneys, and . The hallmark feature of CF is the accumulation of thick mucus in different organs. Long-term issues include difficulty breathing and coughing up mucus as a result of frequent lung . Other signs and symptoms may include sinus infections, poor growth, fatty stool, clubbing of the fingers and toes, and in most males. Different people may have different degrees of symptoms.

Underlined words are explained — tap any of them.

Symptoms — what it feels like

  • ·Difficulty breathing, coughing up mucus, poor growth, fatty stool

Causes — why it happens

  • · ( )

How it's found

  • ·Sweat test, testing

Treatment

  • ·Physiotherapy, , replacement, transmembrane conductance regulator modulators, lung

Outlook

  • ·Life expectancy between 42 and 50 years (developed world)
Plain-language summary adapted from Wikipedia. Not medical advice.