genetic
Severe congenital neutropenia
Severe neutropenia (SCN), also often known as Kostmann or Kostmann disease, is a group of rare disorders that affect myelopoiesis, causing a congenital form of neutropenia, usually without other physical malformations. SCN manifests in infancy with life-threatening . It causes severe pyogenic infections. It can be caused by inheritance of the ELANE gene, autosomal inheritance of the HAX1 gene. There is an increased risk of and myelodysplastic cancers.
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Causes — why it happens
- · in genes, depending on type
How it's found
- ·Blood test, testing
Treatment
- ·G-CSF, HSCT
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See all of Blood →Plain-language summary adapted from Wikipedia. Not medical advice.