D2I2.
genetic

Osteopetrosis

Osteopetrosis, literally 'bone becoming stone', also known as marble bone disease or Albers-Schönberg disease, is an extremely rare inherited disorder whereby the bones harden, becoming denser, in contrast to more prevalent conditions like osteoporosis, in which the bones become less dense and more brittle, or osteomalacia, in which the bones soften. Osteopetrosis can cause bones to dissolve and break.

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Plain-language summary adapted from Wikipedia. Not medical advice.