Neuropathic arthropathy (Charcot joint)

Neuropathic arthropathy, refers to a progressive fragmentation of bones and joints in the presence of neuropathy. It can occur in any joint where denervation is present, although it most frequently presents in the foot and ankle. Charcot's foot develops from an unnoticed trivial bone injury, which will extend with continuing load bearing and, hence, progressing reactive inflammation. This process can be halted by appropriate unloading, preferably before any significant joint damage has occurred. If not, joint coalescence, stiffness and deformity will result, associated with severely impaired foot function. Such a ruined foot will cause considerable morbidity and mortality due to ulceration, infection and amputation.

Underlined words are explained — tap any of them.