genetic
McArdle disease
Glycogen storage disease type V, also known as McArdle's disease, is a disorder, one of the metabolic myopathies, more specifically a muscle glycogen storage disease, caused by a of myophosphorylase. Its is reported as one in 100,000, roughly the same as glycogen storage disease type I.
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Symptoms — what it feels like
- ·Exercise intolerance, inappropriate rapid heart rate response to exercise, exaggerated cardiorespiratory response to exercise, exercise-induced premature muscle and cramping, second wind phenomenon
Causes — why it happens
- · in PYGM gene coding for myophosphorylase
How it's found
- · testing (preferred), muscle . Supplemental tests: blood tests, exercise stress test, 12-minute Walk Test, non-ischemic forearm test, EMG
Complications
- ·Poor physical or mental health due to prolonged delay in , misdiagnosis, or having been given inappropriate exercise advice. Rare include rhabdomyolysis with myoglobinuria requiring hospitalization, transient muscle contracture, and compartment .
More in Muscles
Muscular dystrophyFibromyalgiaMyasthenia gravisTetanusSarcopeniaPolymyositisMuscle crampRhabdomyolysisCompartment syndromeInguinal herniaTendon ruptureDuchenne muscular dystrophy
See all of Muscles →Plain-language summary adapted from Wikipedia. Not medical advice.