D2I2.
genetic

Marfan syndrome

Marfan (MFS) is a multi- disorder that affects the . People with the condition are often tall and thin, with long arms, legs, fingers, and toes. They also typically have exceptionally flexible joints and abnormally curved spines. The most serious involve the heart and aorta, with an increased risk of mitral valve prolapse and . The lungs, eyes, bones, and the covering of the spinal cord are also commonly affected. The severity of the symptoms is variable.

Underlined words are explained — tap any of them.

Symptoms — what it feels like

  • ·Tall thin build; long arms, legs and fingers; flexible fingers and toes

Causes — why it happens

  • · ( )

How it's found

  • ·Ghent criteria and testing (DNA analysis).

Complications

  • ·Scoliosis, mitral valve prolapse,

Outlook

  • ·Often normal life expectancy
Plain-language summary adapted from Wikipedia. Not medical advice.