Inclusion body myositis
Inclusion body myositis (IBM) is the most common muscle disease in older adults. The disease is characterized by slowly progressive weakness and wasting of both muscles and muscles, most apparent in the finger flexors and knee extensors. IBM is often confused with an entirely different class of diseases, called inclusion body myopathies (hIBM). The "M" in hIBM is an abbreviation for "myopathy" while the "M" in IBM is for "myositis". In IBM, two processes appear to occur in the muscles in parallel, one and the other degenerative. is evident from the invasion of muscle fibers by cells. is characterized by the appearance of holes, deposits of abnormal proteins, and filamentous inclusions in the muscle fibers. sIBM is a rare disease, with a ranging from 1 to 71 individuals per million.
Underlined words are explained — tap any of them.
Symptoms — what it feels like
- ·Weakness