D2I2.
genetic

Spondyloepiphyseal dysplasia

Spondyloepiphyseal congenita is a type of dwarfism caused by in the COL2A1 gene. Spondyloepiphyseal dysplasia congenita is present in 1 in 100,000 births, though many children are stillborn, premature, or die shortly after birth. This disorder is characterized by delayed , particularly of the spine and the ends of long bones (epiphyses).

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Plain-language summary adapted from Wikipedia. Not medical advice.