Nail–patella syndrome
Nail–patella is a rare disorder that results in small, poorly developed or deformed nails and — next in order/frequency — hypoplastic kneecaps. A unique feature of this syndrome is the usually triangular — rather than semicircular, as in healthy individuals — lunulae at the base of the fingernails. But nail-patella syndrome can also affect many other areas of the body, such as the elbows, chest, hips and others. The name "nail–patella" can be very misleading, because the syndrome usually is associated simultaneously with many various areas of the body, including even the production of certain proteins. The severity of these effects varies depending on the individual. It is also referred to as iliac horn syndrome, onychoosteodysplasia, Fong disease or Turner–Kieser syndrome. This syndrome is caused by in the LMX1B gene.
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Causes — why it happens
- · in the LMX1B gene.