Merkel cell carcinoma
Merkel cell (MCC) is an aggressive skin cancer occurring in about three thousand persons per year in the United States. It is also known as APUDoma, primary neuroendocrine carcinoma of the skin, primary small-cell carcinoma of the skin, and trabecular carcinoma of the skin. Factors involved in the development of MCC include the Merkel cell polyomavirus, a weakened system, or exposure to ultraviolet . Merkel cell carcinoma usually arises on the head, neck, and , as well as in the perianal region and on the eyelid. It ‘most often presents in an older white population with a male predominance'; 'median age of presentation falls within the late seventh decade, despite a broad age range .’ MCC is less common in children.
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