genetic

Harlequin ichthyosis

Harlequin-type ichthyosis is a disorder that results in thickened skin over nearly the entire body at birth. The skin forms large, diamond/trapezoid/rectangle-shaped plates that are separated by deep cracks. These affect the shape of the eyelids, nose, mouth, and ears and limit movement of the arms and legs. Restricted chest movement can lead to breathing difficulties. These plates fall off over several weeks. Other can include premature birth, , problems with body temperature, and . The condition is the most severe form of ichthyosis, a group of genetic disorders characterised by scaly skin.

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Symptoms — what it feels like

·Very thick skin which cracks, abnormal facial features

Causes — why it happens

· ( )

How it's found

·Based on appearance and testing

Treatment

·Supportive care, moisturizing cream

Complications

·Breathing problems, , problems with body temperature,

Outlook

·Death in the first month is relatively common

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Plain-language summary adapted from Wikipedia. Not medical advice.