{
 "title": "India Whitespace Score",
 "methodology": "Two tiers. Tier 1 (genomically tractable): diseases with a real genomic handle in D2I2 data - a European-calibrated polygenic score whose South-Asian mis-stratification we can measure, a gene set with observed South-Asian pathogenic variants, or a variant with large SAS-vs-EUR frequency divergence. Score = 0.45*IndiaBurden + 0.45*SouthAsianGap + 0.10*Tractability. Tier 2 (descriptive gaps): high India-burden diseases with no verified incidence and no genomic handle - a data gap. Honest limitation: the genomic-handle signal is real only for the diseases our genomics layer covers; the score deliberately concentrates on the tractable frontier, because you can only run a genomics study where a handle exists.",
 "stats": {
  "total_diseases": 1648,
  "tier1_count": 22,
  "tier2_count": 276
 },
 "tier1": [
  {
   "id": "type_2_diabetes",
   "name": "Type 2 diabetes",
   "part": "pancreas",
   "category": "metabolic",
   "india_burden": true,
   "burden": 0.755,
   "tractability": 0.738,
   "sas_gap": 0.918,
   "score": 0.827,
   "handle_types": [
    "prs",
    "common_variant"
   ],
   "signals": {
    "pgs": "PGS000033",
    "worst_sas_pop": "Telugu (India)",
    "misstrat_pct": 30.6,
    "shift_sd": 0.796,
    "direction": "over",
    "freq_divergence": {
     "gene": "MTNR1B",
     "rsid": "rs10830963",
     "sas": 0.4264,
     "eur": 0.2883,
     "gap": 0.138
    }
   },
   "why": "A European-trained polygenic risk score for type 2 diabetes flags 30.6% of Telugu (India) people as high-risk - vs the 10% it was designed for. That's a 3.1x mis-stratification: the score's 'average' is set to European genetics, so it systematically mis-reads South Asians (a +0.80 SD mean shift).",
   "study": "Recalibrate PGS000033 on an Indian cohort (define the threshold on South-Asian, not European, risk) and quantify how many people get correctly re-classified. A concrete, fundable validation study once a genotyped+phenotyped Indian sample is in hand.",
   "learn": "A polygenic risk score adds up many small-effect DNA variants into one risk number. It's calibrated on one ancestry - so its cut-offs drift when applied to another. That drift, not the biology, is what mis-classifies people. This is the core of PRS transferability.",
   "rank": 1
  },
  {
   "id": "cardiomyopathy",
   "name": "Cardiomyopathy",
   "part": "heart",
   "category": "genetic",
   "india_burden": true,
   "burden": 0.583,
   "tractability": 0.7,
   "sas_gap": 1.0,
   "score": 0.782,
   "handle_types": [
    "rare_variant"
   ],
   "signals": {
    "gene_group": "Cardiomyopathy",
    "genes": [
     "LMNA",
     "MYBPC3",
     "MYH7",
     "TNNI3",
     "TNNT2"
    ],
    "sas_observed_pathogenic": 150
   },
   "why": "Across the cardiomyopathy gene set (LMNA, MYBPC3, MYH7, TNNI3, TNNT2), 150 AlphaMissense-'pathogenic' missense variants are actually seen in South Asians (gnomAD) - many European-absent and still clinically 'uncertain'. For cardiomyopathy, that's a pool of computationally-damaging, India-relevant, clinically-unresolved variants no one has systematically characterised.",
   "study": "Take the South-Asian-observed, European-absent, ClinVar-uncertain variants in LMNA, MYBPC3, MYH7, TNNI3, TNNT2 and triage them for cardiomyopathy: functional assays or family segregation to move them from 'uncertain' to a real clinical call. Each reclassified variant is a usable diagnostic result.",
   "learn": "AlphaMissense predicts whether a single amino-acid change is damaging. gnomAD tells you how often it appears - and in which ancestry. 'Damaging + present in South Asians + absent in Europeans + not yet clinically classified' = the highest-value reclassification lead.",
   "rank": 2
  },
  {
   "id": "wilson_s_disease",
   "name": "Wilson's disease",
   "part": "liver",
   "category": "genetic",
   "india_burden": true,
   "burden": 0.583,
   "tractability": 0.7,
   "sas_gap": 0.75,
   "score": 0.67,
   "handle_types": [
    "rare_variant"
   ],
   "signals": {
    "gene_group": "Other high-burden (India)",
    "genes": [
     "ATP7B"
    ],
    "sas_observed_pathogenic": 75
   },
   "why": "Across the other high-burden (india) gene set (ATP7B), 75 AlphaMissense-'pathogenic' missense variants are actually seen in South Asians (gnomAD) - many European-absent and still clinically 'uncertain'. For wilson's disease, that's a pool of computationally-damaging, India-relevant, clinically-unresolved variants no one has systematically characterised.",
   "study": "Take the South-Asian-observed, European-absent, ClinVar-uncertain variants in ATP7B and triage them for wilson's disease: functional assays or family segregation to move them from 'uncertain' to a real clinical call. Each reclassified variant is a usable diagnostic result.",
   "learn": "AlphaMissense predicts whether a single amino-acid change is damaging. gnomAD tells you how often it appears - and in which ancestry. 'Damaging + present in South Asians + absent in Europeans + not yet clinically classified' = the highest-value reclassification lead.",
   "rank": 3
  },
  {
   "id": "coronary_artery_disease",
   "name": "Coronary artery disease",
   "part": "heart",
   "category": "cardiovascular",
   "india_burden": true,
   "burden": 0.59,
   "tractability": 0.8,
   "sas_gap": 0.569,
   "score": 0.602,
   "handle_types": [
    "prs",
    "common_variant"
   ],
   "signals": {
    "pgs": "PGS000010",
    "worst_sas_pop": "Sri Lankan Tamil",
    "misstrat_pct": 0.7,
    "shift_sd": -0.726,
    "direction": "under",
    "freq_divergence": {
     "gene": "VKORC1",
     "rsid": "rs9923231",
     "sas": 0.1452,
     "eur": 0.3877,
     "gap": 0.242
    }
   },
   "why": "A European-trained polygenic risk score for coronary artery disease places only 0.7% of Sri Lankan Tamil people above its high-risk cut-off - far BELOW the 10% it was calibrated to. Yet South Asians carry a well-documented EXCESS of real-world heart disease. The score is blind to South-Asian coronary artery disease genetics: it under-warns exactly the group at higher true risk. This under-flagging is more dangerous than over-flagging.",
   "study": "Build a South-Asian-specific coronary artery disease polygenic score (or recalibrate PGS000010) using Indian genotype+outcome cohorts, then show it recovers the missing high-risk fraction that the European score drops. A clean, publishable recalibration study.",
   "learn": "A polygenic risk score adds up many small-effect DNA variants into one risk number. It's calibrated on one ancestry - so its cut-offs drift when applied to another. That drift, not the biology, is what mis-classifies people. This is the core of PRS transferability.",
   "rank": 4
  },
  {
   "id": "dilated_cardiomyopathy",
   "name": "Dilated cardiomyopathy",
   "part": "heart",
   "category": "cardiovascular",
   "india_burden": false,
   "burden": 0.09,
   "tractability": 0.7,
   "sas_gap": 1.0,
   "score": 0.56,
   "handle_types": [
    "rare_variant"
   ],
   "signals": {
    "gene_group": "Cardiomyopathy",
    "genes": [
     "LMNA",
     "MYBPC3",
     "MYH7",
     "TNNI3",
     "TNNT2"
    ],
    "sas_observed_pathogenic": 150
   },
   "why": "Across the cardiomyopathy gene set (LMNA, MYBPC3, MYH7, TNNI3, TNNT2), 150 AlphaMissense-'pathogenic' missense variants are actually seen in South Asians (gnomAD) - many European-absent and still clinically 'uncertain'. For dilated cardiomyopathy, that's a pool of computationally-damaging, India-relevant, clinically-unresolved variants no one has systematically characterised.",
   "study": "Take the South-Asian-observed, European-absent, ClinVar-uncertain variants in LMNA, MYBPC3, MYH7, TNNI3, TNNT2 and triage them for dilated cardiomyopathy: functional assays or family segregation to move them from 'uncertain' to a real clinical call. Each reclassified variant is a usable diagnostic result.",
   "learn": "AlphaMissense predicts whether a single amino-acid change is damaging. gnomAD tells you how often it appears - and in which ancestry. 'Damaging + present in South Asians + absent in Europeans + not yet clinically classified' = the highest-value reclassification lead.",
   "rank": 5
  },
  {
   "id": "hypertrophic_cardiomyopathy",
   "name": "Hypertrophic cardiomyopathy",
   "part": "heart",
   "category": "genetic",
   "india_burden": false,
   "burden": 0.083,
   "tractability": 0.7,
   "sas_gap": 1.0,
   "score": 0.557,
   "handle_types": [
    "rare_variant"
   ],
   "signals": {
    "gene_group": "Cardiomyopathy",
    "genes": [
     "LMNA",
     "MYBPC3",
     "MYH7",
     "TNNI3",
     "TNNT2"
    ],
    "sas_observed_pathogenic": 150
   },
   "why": "Across the cardiomyopathy gene set (LMNA, MYBPC3, MYH7, TNNI3, TNNT2), 150 AlphaMissense-'pathogenic' missense variants are actually seen in South Asians (gnomAD) - many European-absent and still clinically 'uncertain'. For hypertrophic cardiomyopathy, that's a pool of computationally-damaging, India-relevant, clinically-unresolved variants no one has systematically characterised.",
   "study": "Take the South-Asian-observed, European-absent, ClinVar-uncertain variants in LMNA, MYBPC3, MYH7, TNNI3, TNNT2 and triage them for hypertrophic cardiomyopathy: functional assays or family segregation to move them from 'uncertain' to a real clinical call. Each reclassified variant is a usable diagnostic result.",
   "learn": "AlphaMissense predicts whether a single amino-acid change is damaging. gnomAD tells you how often it appears - and in which ancestry. 'Damaging + present in South Asians + absent in Europeans + not yet clinically classified' = the highest-value reclassification lead.",
   "rank": 6
  },
  {
   "id": "lynch_syndrome",
   "name": "Lynch syndrome",
   "part": "intestines",
   "category": "genetic",
   "india_burden": false,
   "burden": 0.083,
   "tractability": 0.7,
   "sas_gap": 1.0,
   "score": 0.557,
   "handle_types": [
    "rare_variant"
   ],
   "signals": {
    "gene_group": "Hereditary cancer",
    "genes": [
     "BRCA1",
     "BRCA2",
     "MLH1",
     "MSH2",
     "TP53"
    ],
    "sas_observed_pathogenic": 108
   },
   "why": "Across the hereditary cancer gene set (BRCA1, BRCA2, MLH1, MSH2, TP53), 108 AlphaMissense-'pathogenic' missense variants are actually seen in South Asians (gnomAD) - many European-absent and still clinically 'uncertain'. For lynch syndrome, that's a pool of computationally-damaging, India-relevant, clinically-unresolved variants no one has systematically characterised.",
   "study": "Take the South-Asian-observed, European-absent, ClinVar-uncertain variants in BRCA1, BRCA2, MLH1, MSH2, TP53 and triage them for lynch syndrome: functional assays or family segregation to move them from 'uncertain' to a real clinical call. Each reclassified variant is a usable diagnostic result.",
   "learn": "AlphaMissense predicts whether a single amino-acid change is damaging. gnomAD tells you how often it appears - and in which ancestry. 'Damaging + present in South Asians + absent in Europeans + not yet clinically classified' = the highest-value reclassification lead.",
   "rank": 7
  },
  {
   "id": "long_qt_syndrome",
   "name": "Long QT syndrome",
   "part": "heart",
   "category": "genetic",
   "india_burden": false,
   "burden": 0.083,
   "tractability": 0.7,
   "sas_gap": 1.0,
   "score": 0.557,
   "handle_types": [
    "rare_variant"
   ],
   "signals": {
    "gene_group": "Cardiac channelopathy",
    "genes": [
     "KCNH2",
     "KCNQ1",
     "SCN5A"
    ],
    "sas_observed_pathogenic": 125
   },
   "why": "Across the cardiac channelopathy gene set (KCNH2, KCNQ1, SCN5A), 125 AlphaMissense-'pathogenic' missense variants are actually seen in South Asians (gnomAD) - many European-absent and still clinically 'uncertain'. For long qt syndrome, that's a pool of computationally-damaging, India-relevant, clinically-unresolved variants no one has systematically characterised.",
   "study": "Take the South-Asian-observed, European-absent, ClinVar-uncertain variants in KCNH2, KCNQ1, SCN5A and triage them for long qt syndrome: functional assays or family segregation to move them from 'uncertain' to a real clinical call. Each reclassified variant is a usable diagnostic result.",
   "learn": "AlphaMissense predicts whether a single amino-acid change is damaging. gnomAD tells you how often it appears - and in which ancestry. 'Damaging + present in South Asians + absent in Europeans + not yet clinically classified' = the highest-value reclassification lead.",
   "rank": 8
  },
  {
   "id": "brugada_syndrome",
   "name": "Brugada syndrome",
   "part": "heart",
   "category": "genetic",
   "india_burden": false,
   "burden": 0.083,
   "tractability": 0.7,
   "sas_gap": 1.0,
   "score": 0.557,
   "handle_types": [
    "rare_variant"
   ],
   "signals": {
    "gene_group": "Cardiac channelopathy",
    "genes": [
     "KCNH2",
     "KCNQ1",
     "SCN5A"
    ],
    "sas_observed_pathogenic": 125
   },
   "why": "Across the cardiac channelopathy gene set (KCNH2, KCNQ1, SCN5A), 125 AlphaMissense-'pathogenic' missense variants are actually seen in South Asians (gnomAD) - many European-absent and still clinically 'uncertain'. For brugada syndrome, that's a pool of computationally-damaging, India-relevant, clinically-unresolved variants no one has systematically characterised.",
   "study": "Take the South-Asian-observed, European-absent, ClinVar-uncertain variants in KCNH2, KCNQ1, SCN5A and triage them for brugada syndrome: functional assays or family segregation to move them from 'uncertain' to a real clinical call. Each reclassified variant is a usable diagnostic result.",
   "learn": "AlphaMissense predicts whether a single amino-acid change is damaging. gnomAD tells you how often it appears - and in which ancestry. 'Damaging + present in South Asians + absent in Europeans + not yet clinically classified' = the highest-value reclassification lead.",
   "rank": 9
  },
  {
   "id": "glaucoma",
   "name": "Glaucoma",
   "part": "eyes",
   "category": "degenerative",
   "india_burden": true,
   "burden": 0.575,
   "tractability": 0.6,
   "sas_gap": 0.517,
   "score": 0.551,
   "handle_types": [
    "prs"
   ],
   "signals": {
    "pgs": "PGS000350",
    "worst_sas_pop": "Sri Lankan Tamil",
    "misstrat_pct": 20.2,
    "shift_sd": 0.528,
    "direction": "over"
   },
   "why": "A European-trained polygenic risk score for glaucoma flags 20.2% of Sri Lankan Tamil people as high-risk - vs the 10% it was designed for. That's a 2.0x mis-stratification: the score's 'average' is set to European genetics, so it systematically mis-reads South Asians (a +0.53 SD mean shift).",
   "study": "Recalibrate PGS000350 on an Indian cohort (define the threshold on South-Asian, not European, risk) and quantify how many people get correctly re-classified. A concrete, fundable validation study once a genotyped+phenotyped Indian sample is in hand.",
   "learn": "A polygenic risk score adds up many small-effect DNA variants into one risk number. It's calibrated on one ancestry - so its cut-offs drift when applied to another. That drift, not the biology, is what mis-classifies people. This is the core of PRS transferability.",
   "rank": 10
  },
  {
   "id": "ovarian_cancer",
   "name": "Ovarian cancer",
   "part": "repro_f",
   "category": "cancer",
   "india_burden": false,
   "burden": 0.068,
   "tractability": 0.7,
   "sas_gap": 1.0,
   "score": 0.551,
   "handle_types": [
    "rare_variant"
   ],
   "signals": {
    "gene_group": "Hereditary cancer",
    "genes": [
     "BRCA1",
     "BRCA2",
     "MLH1",
     "MSH2",
     "TP53"
    ],
    "sas_observed_pathogenic": 108
   },
   "why": "Across the hereditary cancer gene set (BRCA1, BRCA2, MLH1, MSH2, TP53), 108 AlphaMissense-'pathogenic' missense variants are actually seen in South Asians (gnomAD) - many European-absent and still clinically 'uncertain'. For ovarian cancer, that's a pool of computationally-damaging, India-relevant, clinically-unresolved variants no one has systematically characterised.",
   "study": "Take the South-Asian-observed, European-absent, ClinVar-uncertain variants in BRCA1, BRCA2, MLH1, MSH2, TP53 and triage them for ovarian cancer: functional assays or family segregation to move them from 'uncertain' to a real clinical call. Each reclassified variant is a usable diagnostic result.",
   "learn": "AlphaMissense predicts whether a single amino-acid change is damaging. gnomAD tells you how often it appears - and in which ancestry. 'Damaging + present in South Asians + absent in Europeans + not yet clinically classified' = the highest-value reclassification lead.",
   "rank": 11
  },
  {
   "id": "colorectal_cancer",
   "name": "Colorectal cancer",
   "part": "intestines",
   "category": "cancer",
   "india_burden": false,
   "burden": 0.068,
   "tractability": 0.7,
   "sas_gap": 1.0,
   "score": 0.551,
   "handle_types": [
    "rare_variant"
   ],
   "signals": {
    "gene_group": "Hereditary cancer",
    "genes": [
     "BRCA1",
     "BRCA2",
     "MLH1",
     "MSH2",
     "TP53"
    ],
    "sas_observed_pathogenic": 108
   },
   "why": "Across the hereditary cancer gene set (BRCA1, BRCA2, MLH1, MSH2, TP53), 108 AlphaMissense-'pathogenic' missense variants are actually seen in South Asians (gnomAD) - many European-absent and still clinically 'uncertain'. For colorectal cancer, that's a pool of computationally-damaging, India-relevant, clinically-unresolved variants no one has systematically characterised.",
   "study": "Take the South-Asian-observed, European-absent, ClinVar-uncertain variants in BRCA1, BRCA2, MLH1, MSH2, TP53 and triage them for colorectal cancer: functional assays or family segregation to move them from 'uncertain' to a real clinical call. Each reclassified variant is a usable diagnostic result.",
   "learn": "AlphaMissense predicts whether a single amino-acid change is damaging. gnomAD tells you how often it appears - and in which ancestry. 'Damaging + present in South Asians + absent in Europeans + not yet clinically classified' = the highest-value reclassification lead.",
   "rank": 12
  },
  {
   "id": "dyslipidaemia_high_cholesterol",
   "name": "Dyslipidaemia (high cholesterol)",
   "part": "thyroid",
   "category": "metabolic",
   "india_burden": true,
   "burden": 0.59,
   "tractability": 0.6,
   "sas_gap": 0.35,
   "score": 0.483,
   "handle_types": [
    "prs"
   ],
   "signals": {
    "pgs": "PGS000061",
    "worst_sas_pop": "Gujarati",
    "misstrat_pct": 16.4,
    "shift_sd": 0.395,
    "direction": "over"
   },
   "why": "A European-trained polygenic risk score for dyslipidaemia (high cholesterol) flags 16.4% of Gujarati people as high-risk - vs the 10% it was designed for. That's a 1.6x mis-stratification: the score's 'average' is set to European genetics, so it systematically mis-reads South Asians (a +0.40 SD mean shift).",
   "study": "Recalibrate PGS000061 on an Indian cohort (define the threshold on South-Asian, not European, risk) and quantify how many people get correctly re-classified. A concrete, fundable validation study once a genotyped+phenotyped Indian sample is in hand.",
   "learn": "A polygenic risk score adds up many small-effect DNA variants into one risk number. It's calibrated on one ancestry - so its cut-offs drift when applied to another. That drift, not the biology, is what mis-classifies people. This is the core of PRS transferability.",
   "rank": 13
  },
  {
   "id": "breast_cancer",
   "name": "Breast cancer",
   "part": "repro_f",
   "category": "cancer",
   "india_burden": true,
   "burden": 0.568,
   "tractability": 0.6,
   "sas_gap": 0.361,
   "score": 0.478,
   "handle_types": [
    "prs"
   ],
   "signals": {
    "pgs": "PGS000047",
    "worst_sas_pop": "Bengali",
    "misstrat_pct": 17.3,
    "shift_sd": 0.355,
    "direction": "over"
   },
   "why": "A European-trained polygenic risk score for breast cancer flags 17.3% of Bengali people as high-risk - vs the 10% it was designed for. That's a 1.7x mis-stratification: the score's 'average' is set to European genetics, so it systematically mis-reads South Asians (a +0.35 SD mean shift).",
   "study": "Recalibrate PGS000047 on an Indian cohort (define the threshold on South-Asian, not European, risk) and quantify how many people get correctly re-classified. A concrete, fundable validation study once a genotyped+phenotyped Indian sample is in hand.",
   "learn": "A polygenic risk score adds up many small-effect DNA variants into one risk number. It's calibrated on one ancestry - so its cut-offs drift when applied to another. That drift, not the biology, is what mis-classifies people. This is the core of PRS transferability.",
   "rank": 14
  },
  {
   "id": "prostate_cancer",
   "name": "Prostate cancer",
   "part": "repro_m",
   "category": "cancer",
   "india_burden": false,
   "burden": 0.068,
   "tractability": 0.6,
   "sas_gap": 0.852,
   "score": 0.474,
   "handle_types": [
    "prs"
   ],
   "signals": {
    "pgs": "PGS000067",
    "worst_sas_pop": "Punjabi (Lahore)",
    "misstrat_pct": 29.4,
    "shift_sd": 0.674,
    "direction": "over"
   },
   "why": "A European-trained polygenic risk score for prostate cancer flags 29.4% of Punjabi (Lahore) people as high-risk - vs the 10% it was designed for. That's a 2.9x mis-stratification: the score's 'average' is set to European genetics, so it systematically mis-reads South Asians (a +0.67 SD mean shift).",
   "study": "Recalibrate PGS000067 on an Indian cohort (define the threshold on South-Asian, not European, risk) and quantify how many people get correctly re-classified. A concrete, fundable validation study once a genotyped+phenotyped Indian sample is in hand.",
   "learn": "A polygenic risk score adds up many small-effect DNA variants into one risk number. It's calibrated on one ancestry - so its cut-offs drift when applied to another. That drift, not the biology, is what mis-classifies people. This is the core of PRS transferability.",
   "rank": 15
  },
  {
   "id": "familial_hypercholesterolaemia",
   "name": "Familial hypercholesterolaemia",
   "part": "thyroid",
   "category": "genetic",
   "india_burden": false,
   "burden": 0.083,
   "tractability": 0.7,
   "sas_gap": 0.75,
   "score": 0.445,
   "handle_types": [
    "rare_variant"
   ],
   "signals": {
    "gene_group": "Familial hypercholesterolemia",
    "genes": [
     "APOB",
     "LDLR",
     "PCSK9"
    ],
    "sas_observed_pathogenic": 75
   },
   "why": "Across the familial hypercholesterolemia gene set (APOB, LDLR, PCSK9), 75 AlphaMissense-'pathogenic' missense variants are actually seen in South Asians (gnomAD) - many European-absent and still clinically 'uncertain'. For familial hypercholesterolaemia, that's a pool of computationally-damaging, India-relevant, clinically-unresolved variants no one has systematically characterised.",
   "study": "Take the South-Asian-observed, European-absent, ClinVar-uncertain variants in APOB, LDLR, PCSK9 and triage them for familial hypercholesterolaemia: functional assays or family segregation to move them from 'uncertain' to a real clinical call. Each reclassified variant is a usable diagnostic result.",
   "learn": "AlphaMissense predicts whether a single amino-acid change is damaging. gnomAD tells you how often it appears - and in which ancestry. 'Damaging + present in South Asians + absent in Europeans + not yet clinically classified' = the highest-value reclassification lead.",
   "rank": 16
  },
  {
   "id": "hearing_loss",
   "name": "Hearing loss",
   "part": "ears",
   "category": "common",
   "india_burden": true,
   "burden": 0.56,
   "tractability": 0.527,
   "sas_gap": 0.19,
   "score": 0.39,
   "handle_types": [
    "rare_variant"
   ],
   "signals": {
    "gene_group": "Other high-burden (India)",
    "genes": [
     "GJB2"
    ],
    "sas_observed_pathogenic": 19
   },
   "why": "Across the other high-burden (india) gene set (GJB2), 19 AlphaMissense-'pathogenic' missense variants are actually seen in South Asians (gnomAD) - many European-absent and still clinically 'uncertain'. For hearing loss, that's a pool of computationally-damaging, India-relevant, clinically-unresolved variants no one has systematically characterised.",
   "study": "Take the South-Asian-observed, European-absent, ClinVar-uncertain variants in GJB2 and triage them for hearing loss: functional assays or family segregation to move them from 'uncertain' to a real clinical call. Each reclassified variant is a usable diagnostic result.",
   "learn": "AlphaMissense predicts whether a single amino-acid change is damaging. gnomAD tells you how often it appears - and in which ancestry. 'Damaging + present in South Asians + absent in Europeans + not yet clinically classified' = the highest-value reclassification lead.",
   "rank": 17
  },
  {
   "id": "g6pd_deficiency",
   "name": "G6PD deficiency",
   "part": "blood",
   "category": "genetic",
   "india_burden": true,
   "burden": 0.583,
   "tractability": 0.513,
   "sas_gap": 0.17,
   "score": 0.39,
   "handle_types": [
    "rare_variant"
   ],
   "signals": {
    "gene_group": "Other high-burden (India)",
    "genes": [
     "G6PD"
    ],
    "sas_observed_pathogenic": 17
   },
   "why": "Across the other high-burden (india) gene set (G6PD), 17 AlphaMissense-'pathogenic' missense variants are actually seen in South Asians (gnomAD) - many European-absent and still clinically 'uncertain'. For g6pd deficiency, that's a pool of computationally-damaging, India-relevant, clinically-unresolved variants no one has systematically characterised.",
   "study": "Take the South-Asian-observed, European-absent, ClinVar-uncertain variants in G6PD and triage them for g6pd deficiency: functional assays or family segregation to move them from 'uncertain' to a real clinical call. Each reclassified variant is a usable diagnostic result.",
   "learn": "AlphaMissense predicts whether a single amino-acid change is damaging. gnomAD tells you how often it appears - and in which ancestry. 'Damaging + present in South Asians + absent in Europeans + not yet clinically classified' = the highest-value reclassification lead.",
   "rank": 18
  },
  {
   "id": "beta_thalassemia",
   "name": "Beta-thalassemia",
   "part": "blood",
   "category": "genetic",
   "india_burden": true,
   "burden": 0.583,
   "tractability": 0.433,
   "sas_gap": 0.05,
   "score": 0.328,
   "handle_types": [
    "rare_variant"
   ],
   "signals": {
    "gene_group": "Other high-burden (India)",
    "genes": [
     "HBB"
    ],
    "sas_observed_pathogenic": 5
   },
   "why": "Across the other high-burden (india) gene set (HBB), 5 AlphaMissense-'pathogenic' missense variants are actually seen in South Asians (gnomAD) - many European-absent and still clinically 'uncertain'. For beta-thalassemia, that's a pool of computationally-damaging, India-relevant, clinically-unresolved variants no one has systematically characterised.",
   "study": "Take the South-Asian-observed, European-absent, ClinVar-uncertain variants in HBB and triage them for beta-thalassemia: functional assays or family segregation to move them from 'uncertain' to a real clinical call. Each reclassified variant is a usable diagnostic result.",
   "learn": "AlphaMissense predicts whether a single amino-acid change is damaging. gnomAD tells you how often it appears - and in which ancestry. 'Damaging + present in South Asians + absent in Europeans + not yet clinically classified' = the highest-value reclassification lead.",
   "rank": 19
  },
  {
   "id": "sickle_cell_disease",
   "name": "Sickle cell disease",
   "part": "blood",
   "category": "genetic",
   "india_burden": true,
   "burden": 0.583,
   "tractability": 0.433,
   "sas_gap": 0.05,
   "score": 0.328,
   "handle_types": [
    "rare_variant"
   ],
   "signals": {
    "gene_group": "Other high-burden (India)",
    "genes": [
     "HBB"
    ],
    "sas_observed_pathogenic": 5
   },
   "why": "Across the other high-burden (india) gene set (HBB), 5 AlphaMissense-'pathogenic' missense variants are actually seen in South Asians (gnomAD) - many European-absent and still clinically 'uncertain'. For sickle cell disease, that's a pool of computationally-damaging, India-relevant, clinically-unresolved variants no one has systematically characterised.",
   "study": "Take the South-Asian-observed, European-absent, ClinVar-uncertain variants in HBB and triage them for sickle cell disease: functional assays or family segregation to move them from 'uncertain' to a real clinical call. Each reclassified variant is a usable diagnostic result.",
   "learn": "AlphaMissense predicts whether a single amino-acid change is damaging. gnomAD tells you how often it appears - and in which ancestry. 'Damaging + present in South Asians + absent in Europeans + not yet clinically classified' = the highest-value reclassification lead.",
   "rank": 20
  },
  {
   "id": "thalassaemia",
   "name": "Thalassaemia",
   "part": "blood",
   "category": "genetic",
   "india_burden": true,
   "burden": 0.583,
   "tractability": 0.433,
   "sas_gap": 0.05,
   "score": 0.328,
   "handle_types": [
    "rare_variant"
   ],
   "signals": {
    "gene_group": "Other high-burden (India)",
    "genes": [
     "HBB"
    ],
    "sas_observed_pathogenic": 5
   },
   "why": "Across the other high-burden (india) gene set (HBB), 5 AlphaMissense-'pathogenic' missense variants are actually seen in South Asians (gnomAD) - many European-absent and still clinically 'uncertain'. For thalassaemia, that's a pool of computationally-damaging, India-relevant, clinically-unresolved variants no one has systematically characterised.",
   "study": "Take the South-Asian-observed, European-absent, ClinVar-uncertain variants in HBB and triage them for thalassaemia: functional assays or family segregation to move them from 'uncertain' to a real clinical call. Each reclassified variant is a usable diagnostic result.",
   "learn": "AlphaMissense predicts whether a single amino-acid change is damaging. gnomAD tells you how often it appears - and in which ancestry. 'Damaging + present in South Asians + absent in Europeans + not yet clinically classified' = the highest-value reclassification lead.",
   "rank": 21
  },
  {
   "id": "mody_mature_onset_diabetes_of_the_young",
   "name": "MODY (mature-onset diabetes of the young)",
   "part": "pancreas",
   "category": "genetic",
   "india_burden": false,
   "burden": 0.083,
   "tractability": 0.653,
   "sas_gap": 0.38,
   "score": 0.274,
   "handle_types": [
    "rare_variant"
   ],
   "signals": {
    "gene_group": "Monogenic diabetes (MODY)",
    "genes": [
     "GCK",
     "HNF1A",
     "HNF4A"
    ],
    "sas_observed_pathogenic": 38
   },
   "why": "Across the monogenic diabetes (mody) gene set (GCK, HNF1A, HNF4A), 38 AlphaMissense-'pathogenic' missense variants are actually seen in South Asians (gnomAD) - many European-absent and still clinically 'uncertain'. For mody (mature-onset diabetes of the young), that's a pool of computationally-damaging, India-relevant, clinically-unresolved variants no one has systematically characterised.",
   "study": "Take the South-Asian-observed, European-absent, ClinVar-uncertain variants in GCK, HNF1A, HNF4A and triage them for mody (mature-onset diabetes of the young): functional assays or family segregation to move them from 'uncertain' to a real clinical call. Each reclassified variant is a usable diagnostic result.",
   "learn": "AlphaMissense predicts whether a single amino-acid change is damaging. gnomAD tells you how often it appears - and in which ancestry. 'Damaging + present in South Asians + absent in Europeans + not yet clinically classified' = the highest-value reclassification lead.",
   "rank": 22
  }
 ],
 "tier2": [
  {
   "id": "subacute_combined_degeneration",
   "name": "Subacute combined degeneration",
   "part": "brain",
   "category": "nutritional",
   "burden": 0.635,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "night_blindness_vitamin_a",
   "name": "Night blindness (Vitamin A)",
   "part": "eyes",
   "category": "nutritional",
   "burden": 0.635,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "plummer_vinson_syndrome",
   "name": "Plummer–Vinson syndrome",
   "part": "mouth",
   "category": "nutritional",
   "burden": 0.635,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "iodine_deficiency",
   "name": "Iodine deficiency",
   "part": "thyroid",
   "category": "nutritional",
   "burden": 0.635,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "marasmus",
   "name": "Marasmus",
   "part": "intestines",
   "category": "nutritional",
   "burden": 0.635,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "kwashiorkor",
   "name": "Kwashiorkor",
   "part": "intestines",
   "category": "nutritional",
   "burden": 0.635,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "protein_energy_malnutrition",
   "name": "Protein–energy malnutrition",
   "part": "intestines",
   "category": "nutritional",
   "burden": 0.635,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "rickets_osteomalacia",
   "name": "Rickets / osteomalacia",
   "part": "bones",
   "category": "nutritional",
   "burden": 0.635,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "vitamin_d_deficiency",
   "name": "Vitamin D deficiency",
   "part": "bones",
   "category": "nutritional",
   "burden": 0.635,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "osteomalacia",
   "name": "Osteomalacia",
   "part": "bones",
   "category": "nutritional",
   "burden": 0.635,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "vitamin_b12_deficiency",
   "name": "Vitamin B12 deficiency",
   "part": "blood",
   "category": "nutritional",
   "burden": 0.635,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "folate_deficiency_anaemia",
   "name": "Folate-deficiency anaemia",
   "part": "blood",
   "category": "nutritional",
   "burden": 0.635,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "zinc_deficiency",
   "name": "Zinc deficiency",
   "part": "blood",
   "category": "nutritional",
   "burden": 0.635,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "megaloblastic_anaemia",
   "name": "Megaloblastic anaemia",
   "part": "blood",
   "category": "nutritional",
   "burden": 0.635,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "meningitis",
   "name": "Meningitis",
   "part": "brain",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "japanese_encephalitis",
   "name": "Japanese encephalitis",
   "part": "brain",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "encephalitis",
   "name": "Encephalitis",
   "part": "brain",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "neurocysticercosis",
   "name": "Neurocysticercosis",
   "part": "brain",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "subacute_sclerosing_panencephalitis",
   "name": "Subacute sclerosing panencephalitis",
   "part": "brain",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "sydenham_s_chorea",
   "name": "Sydenham's chorea",
   "part": "brain",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "trachoma",
   "name": "Trachoma",
   "part": "eyes",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "corneal_ulcer",
   "name": "Corneal ulcer",
   "part": "eyes",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "keratitis",
   "name": "Keratitis",
   "part": "eyes",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "dacryocystitis",
   "name": "Dacryocystitis",
   "part": "eyes",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "cytomegalovirus_retinitis",
   "name": "Cytomegalovirus retinitis",
   "part": "eyes",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "fungal_keratitis",
   "name": "Fungal keratitis",
   "part": "eyes",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "acanthamoeba_keratitis",
   "name": "Acanthamoeba keratitis",
   "part": "eyes",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "otitis_media_ear_infection",
   "name": "Otitis media (ear infection)",
   "part": "ears",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "sinusitis",
   "name": "Sinusitis",
   "part": "ears",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "otomycosis",
   "name": "Otomycosis",
   "part": "ears",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "rhinoscleroma",
   "name": "Rhinoscleroma",
   "part": "ears",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "rhinosporidiosis",
   "name": "Rhinosporidiosis",
   "part": "ears",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "dental_abscess",
   "name": "Dental abscess",
   "part": "mouth",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "pharyngitis_sore_throat",
   "name": "Pharyngitis (sore throat)",
   "part": "mouth",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "ludwig_s_angina",
   "name": "Ludwig's angina",
   "part": "mouth",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "noma",
   "name": "Noma",
   "part": "mouth",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "rheumatic_heart_disease",
   "name": "Rheumatic heart disease",
   "part": "heart",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "pneumonia",
   "name": "Pneumonia",
   "part": "lungs",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "influenza",
   "name": "Influenza",
   "part": "lungs",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "mucormycosis_black_fungus",
   "name": "Mucormycosis (black fungus)",
   "part": "lungs",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "nipah_virus_infection",
   "name": "Nipah virus infection",
   "part": "lungs",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "empyema",
   "name": "Empyema",
   "part": "lungs",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "aspergillosis",
   "name": "Aspergillosis",
   "part": "lungs",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "lung_abscess",
   "name": "Lung abscess",
   "part": "lungs",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "aspiration_pneumonia",
   "name": "Aspiration pneumonia",
   "part": "lungs",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "aspergilloma",
   "name": "Aspergilloma",
   "part": "lungs",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "hepatitis_a",
   "name": "Hepatitis A",
   "part": "liver",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "hepatitis_e",
   "name": "Hepatitis E",
   "part": "liver",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "amoebic_liver_abscess",
   "name": "Amoebic liver abscess",
   "part": "liver",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "hydatid_disease",
   "name": "Hydatid disease",
   "part": "liver",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "pyogenic_liver_abscess",
   "name": "Pyogenic liver abscess",
   "part": "liver",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "h_pylori_infection",
   "name": "H. pylori infection",
   "part": "gi",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "gastroenteritis",
   "name": "Gastroenteritis",
   "part": "gi",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "food_poisoning",
   "name": "Food poisoning",
   "part": "gi",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "salmonellosis",
   "name": "Salmonellosis",
   "part": "gi",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "stomach_flu_rotavirus",
   "name": "Stomach flu (rotavirus)",
   "part": "gi",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "typhoid_fever",
   "name": "Typhoid fever",
   "part": "intestines",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "intestinal_worms",
   "name": "Intestinal worms",
   "part": "intestines",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "amoebiasis",
   "name": "Amoebiasis",
   "part": "intestines",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "cholera",
   "name": "Cholera",
   "part": "intestines",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "giardiasis",
   "name": "Giardiasis",
   "part": "intestines",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "hookworm_infection",
   "name": "Hookworm infection",
   "part": "intestines",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "ascariasis",
   "name": "Ascariasis",
   "part": "intestines",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "tapeworm_infection",
   "name": "Tapeworm infection",
   "part": "intestines",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "shigellosis_dysentery",
   "name": "Shigellosis (dysentery)",
   "part": "intestines",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "intestinal_tuberculosis",
   "name": "Intestinal tuberculosis",
   "part": "intestines",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "whipworm_trichuriasis",
   "name": "Whipworm (trichuriasis)",
   "part": "intestines",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "strongyloidiasis",
   "name": "Strongyloidiasis",
   "part": "intestines",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "cryptosporidiosis",
   "name": "Cryptosporidiosis",
   "part": "intestines",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "pinworm_infection",
   "name": "Pinworm infection",
   "part": "intestines",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "guinea_worm_disease",
   "name": "Guinea worm disease",
   "part": "intestines",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "toxocariasis",
   "name": "Toxocariasis",
   "part": "intestines",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "urinary_tract_infection",
   "name": "Urinary tract infection",
   "part": "bladder",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "syphilis",
   "name": "Syphilis",
   "part": "repro_f",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "gonorrhoea",
   "name": "Gonorrhoea",
   "part": "repro_f",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "genital_warts_hpv",
   "name": "Genital warts (HPV)",
   "part": "repro_f",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "endometritis",
   "name": "Endometritis",
   "part": "repro_f",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "pyometra",
   "name": "Pyometra",
   "part": "repro_f",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "tubo_ovarian_abscess",
   "name": "Tubo-ovarian abscess",
   "part": "repro_f",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "chancroid",
   "name": "Chancroid",
   "part": "repro_m",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "fungal_skin_infection",
   "name": "Fungal skin infection",
   "part": "skin",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "leprosy",
   "name": "Leprosy",
   "part": "skin",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "scabies",
   "name": "Scabies",
   "part": "skin",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "cellulitis",
   "name": "Cellulitis",
   "part": "skin",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "impetigo",
   "name": "Impetigo",
   "part": "skin",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "tinea_versicolor",
   "name": "Tinea versicolor",
   "part": "skin",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "boils_furuncles",
   "name": "Boils (furuncles)",
   "part": "skin",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "madura_foot_mycetoma",
   "name": "Madura foot (mycetoma)",
   "part": "skin",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "donovanosis",
   "name": "Donovanosis",
   "part": "skin",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "cutaneous_larva_migrans",
   "name": "Cutaneous larva migrans",
   "part": "skin",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "spinal_tb_pott_s_disease",
   "name": "Spinal TB (Pott's disease)",
   "part": "bones",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "tetanus",
   "name": "Tetanus",
   "part": "muscles",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "pyomyositis",
   "name": "Pyomyositis",
   "part": "muscles",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "dengue_fever",
   "name": "Dengue fever",
   "part": "immune",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "chikungunya",
   "name": "Chikungunya",
   "part": "immune",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "covid_19",
   "name": "COVID-19",
   "part": "immune",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "measles",
   "name": "Measles",
   "part": "immune",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "rabies",
   "name": "Rabies",
   "part": "immune",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "kala_azar_visceral_leishmaniasis",
   "name": "Kala-azar (visceral leishmaniasis)",
   "part": "immune",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "lymphatic_filariasis",
   "name": "Lymphatic filariasis",
   "part": "immune",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "leptospirosis",
   "name": "Leptospirosis",
   "part": "immune",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "scrub_typhus",
   "name": "Scrub typhus",
   "part": "immune",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "diphtheria",
   "name": "Diphtheria",
   "part": "immune",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "poliomyelitis",
   "name": "Poliomyelitis",
   "part": "immune",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "plague",
   "name": "Plague",
   "part": "immune",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "brucellosis",
   "name": "Brucellosis",
   "part": "immune",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "melioidosis",
   "name": "Melioidosis",
   "part": "immune",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "cutaneous_leishmaniasis",
   "name": "Cutaneous leishmaniasis",
   "part": "immune",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "indian_tick_typhus",
   "name": "Indian tick typhus",
   "part": "immune",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "kyasanur_forest_disease_monkey_fever",
   "name": "Kyasanur Forest disease (monkey fever)",
   "part": "immune",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "crimean_congo_haemorrhagic_fever",
   "name": "Crimean–Congo haemorrhagic fever",
   "part": "immune",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "mpox_monkeypox",
   "name": "Mpox (monkeypox)",
   "part": "immune",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "west_nile_fever",
   "name": "West Nile fever",
   "part": "immune",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "rubella_german_measles",
   "name": "Rubella (German measles)",
   "part": "immune",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "gas_gangrene",
   "name": "Gas gangrene",
   "part": "immune",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "roseola",
   "name": "Roseola",
   "part": "immune",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "mycobacterium_avium_complex_infection",
   "name": "Mycobacterium avium complex infection",
   "part": "immune",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "tropical_pulmonary_eosinophilia",
   "name": "Tropical pulmonary eosinophilia",
   "part": "immune",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "murine_typhus",
   "name": "Murine typhus",
   "part": "immune",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "rat_bite_fever",
   "name": "Rat-bite fever",
   "part": "immune",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "yaws",
   "name": "Yaws",
   "part": "immune",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "chromoblastomycosis",
   "name": "Chromoblastomycosis",
   "part": "immune",
   "category": "infection",
   "burden": 0.627,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "metabolic_syndrome",
   "name": "Metabolic syndrome",
   "part": "thyroid",
   "category": "metabolic",
   "burden": 0.59,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "insulin_resistance",
   "name": "Insulin resistance",
   "part": "thyroid",
   "category": "metabolic",
   "burden": 0.59,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "heart_failure",
   "name": "Heart failure",
   "part": "heart",
   "category": "cardiovascular",
   "burden": 0.59,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "angina",
   "name": "Angina",
   "part": "heart",
   "category": "cardiovascular",
   "burden": 0.59,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "fatty_liver_disease",
   "name": "Fatty liver disease",
   "part": "liver",
   "category": "metabolic",
   "burden": 0.59,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "gestational_diabetes",
   "name": "Gestational diabetes",
   "part": "pancreas",
   "category": "metabolic",
   "burden": 0.59,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "down_syndrome",
   "name": "Down syndrome",
   "part": "brain",
   "category": "genetic",
   "burden": 0.583,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "congenital_adrenal_hyperplasia",
   "name": "Congenital adrenal hyperplasia",
   "part": "thyroid",
   "category": "genetic",
   "burden": 0.583,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "albinism",
   "name": "Albinism",
   "part": "skin",
   "category": "genetic",
   "burden": 0.583,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "sickle_cell_trait",
   "name": "Sickle cell trait",
   "part": "blood",
   "category": "genetic",
   "burden": 0.583,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "haemoglobin_e_disease",
   "name": "Haemoglobin E disease",
   "part": "blood",
   "category": "genetic",
   "burden": 0.583,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "alpha_thalassemia",
   "name": "Alpha-thalassemia",
   "part": "blood",
   "category": "genetic",
   "burden": 0.583,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "hemoglobin_d_disease",
   "name": "Hemoglobin D disease",
   "part": "blood",
   "category": "genetic",
   "burden": 0.583,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "stroke",
   "name": "Stroke",
   "part": "brain",
   "category": "vascular",
   "burden": 0.575,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "cerebral_venous_sinus_thrombosis",
   "name": "Cerebral venous sinus thrombosis",
   "part": "brain",
   "category": "vascular",
   "burden": 0.575,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "cataract",
   "name": "Cataract",
   "part": "eyes",
   "category": "degenerative",
   "burden": 0.575,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "hypertensive_retinopathy",
   "name": "Hypertensive retinopathy",
   "part": "eyes",
   "category": "vascular",
   "burden": 0.575,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "osteoporosis",
   "name": "Osteoporosis",
   "part": "bones",
   "category": "degenerative",
   "burden": 0.575,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "cervical_spondylosis",
   "name": "Cervical spondylosis",
   "part": "bones",
   "category": "degenerative",
   "burden": 0.575,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "osteoarthritis",
   "name": "Osteoarthritis",
   "part": "joints",
   "category": "degenerative",
   "burden": 0.575,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "retinoblastoma",
   "name": "Retinoblastoma",
   "part": "eyes",
   "category": "cancer",
   "burden": 0.568,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "oral_cancer",
   "name": "Oral cancer",
   "part": "mouth",
   "category": "cancer",
   "burden": 0.568,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "laryngeal_cancer",
   "name": "Laryngeal cancer",
   "part": "mouth",
   "category": "cancer",
   "burden": 0.568,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "nasopharyngeal_carcinoma",
   "name": "Nasopharyngeal carcinoma",
   "part": "mouth",
   "category": "cancer",
   "burden": 0.568,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "verrucous_carcinoma",
   "name": "Verrucous carcinoma",
   "part": "mouth",
   "category": "cancer",
   "burden": 0.568,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "cholangiocarcinoma",
   "name": "Cholangiocarcinoma",
   "part": "liver",
   "category": "cancer",
   "burden": 0.568,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "gallbladder_cancer",
   "name": "Gallbladder cancer",
   "part": "gi",
   "category": "cancer",
   "burden": 0.568,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "cervical_cancer",
   "name": "Cervical cancer",
   "part": "repro_f",
   "category": "cancer",
   "burden": 0.568,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "penile_cancer",
   "name": "Penile cancer",
   "part": "repro_m",
   "category": "cancer",
   "burden": 0.568,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "sciatica",
   "name": "Sciatica",
   "part": "brain",
   "category": "common",
   "burden": 0.56,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "insomnia",
   "name": "Insomnia",
   "part": "brain",
   "category": "common",
   "burden": 0.56,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "tension_headache",
   "name": "Tension headache",
   "part": "brain",
   "category": "common",
   "burden": 0.56,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "spina_bifida",
   "name": "Spina bifida",
   "part": "brain",
   "category": "congenital",
   "burden": 0.56,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "refractive_error_myopia",
   "name": "Refractive error (myopia)",
   "part": "eyes",
   "category": "common",
   "burden": 0.56,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "presbyopia",
   "name": "Presbyopia",
   "part": "eyes",
   "category": "common",
   "burden": 0.56,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "pterygium",
   "name": "Pterygium",
   "part": "eyes",
   "category": "common",
   "burden": 0.56,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "deviated_nasal_septum",
   "name": "Deviated nasal septum",
   "part": "ears",
   "category": "common",
   "burden": 0.56,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "perforated_eardrum",
   "name": "Perforated eardrum",
   "part": "ears",
   "category": "common",
   "burden": 0.56,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "dental_caries_cavities",
   "name": "Dental caries (cavities)",
   "part": "mouth",
   "category": "common",
   "burden": 0.56,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "gum_disease_periodontitis",
   "name": "Gum disease (periodontitis)",
   "part": "mouth",
   "category": "common",
   "burden": 0.56,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "cleft_lip_and_palate",
   "name": "Cleft lip and palate",
   "part": "mouth",
   "category": "congenital",
   "burden": 0.56,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "gingivitis",
   "name": "Gingivitis",
   "part": "mouth",
   "category": "common",
   "burden": 0.56,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "pulpitis",
   "name": "Pulpitis",
   "part": "mouth",
   "category": "common",
   "burden": 0.56,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "congenital_hypothyroidism",
   "name": "Congenital hypothyroidism",
   "part": "thyroid",
   "category": "congenital",
   "burden": 0.56,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "thyroid_nodule",
   "name": "Thyroid nodule",
   "part": "thyroid",
   "category": "common",
   "burden": 0.56,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "ventricular_septal_defect",
   "name": "Ventricular septal defect",
   "part": "heart",
   "category": "congenital",
   "burden": 0.56,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "takayasu_arteritis",
   "name": "Takayasu arteritis",
   "part": "vessels",
   "category": "autoimmune",
   "burden": 0.56,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "jaundice",
   "name": "Jaundice",
   "part": "liver",
   "category": "common",
   "burden": 0.56,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "biliary_atresia",
   "name": "Biliary atresia",
   "part": "liver",
   "category": "congenital",
   "burden": 0.56,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "choledochal_cyst",
   "name": "Choledochal cyst",
   "part": "liver",
   "category": "congenital",
   "burden": 0.56,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "peptic_ulcer",
   "name": "Peptic ulcer",
   "part": "gi",
   "category": "common",
   "burden": 0.56,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "lactose_intolerance",
   "name": "Lactose intolerance",
   "part": "intestines",
   "category": "common",
   "burden": 0.56,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "anal_fistula",
   "name": "Anal fistula",
   "part": "intestines",
   "category": "common",
   "burden": 0.56,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "kidney_stones",
   "name": "Kidney stones",
   "part": "kidneys",
   "category": "common",
   "burden": 0.56,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "iga_nephropathy",
   "name": "IgA nephropathy",
   "part": "kidneys",
   "category": "autoimmune",
   "burden": 0.56,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "nephrolithiasis_stones",
   "name": "Nephrolithiasis (stones)",
   "part": "kidneys",
   "category": "common",
   "burden": 0.56,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "bladder_stones",
   "name": "Bladder stones",
   "part": "bladder",
   "category": "common",
   "burden": 0.56,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "cystocele",
   "name": "Cystocele",
   "part": "bladder",
   "category": "common",
   "burden": 0.56,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "bladder_outlet_obstruction",
   "name": "Bladder outlet obstruction",
   "part": "bladder",
   "category": "common",
   "burden": 0.56,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "painful_periods_dysmenorrhea",
   "name": "Painful periods (dysmenorrhea)",
   "part": "repro_f",
   "category": "common",
   "burden": 0.56,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "ovarian_cyst",
   "name": "Ovarian cyst",
   "part": "repro_f",
   "category": "common",
   "burden": 0.56,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "heavy_periods_menorrhagia",
   "name": "Heavy periods (menorrhagia)",
   "part": "repro_f",
   "category": "common",
   "burden": 0.56,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "pelvic_organ_prolapse",
   "name": "Pelvic organ prolapse",
   "part": "repro_f",
   "category": "common",
   "burden": 0.56,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "hydrocele",
   "name": "Hydrocele",
   "part": "repro_m",
   "category": "common",
   "burden": 0.56,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "azoospermia",
   "name": "Azoospermia",
   "part": "repro_m",
   "category": "common",
   "burden": 0.56,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "oligospermia",
   "name": "Oligospermia",
   "part": "repro_m",
   "category": "common",
   "burden": 0.56,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "acne",
   "name": "Acne",
   "part": "skin",
   "category": "common",
   "burden": 0.56,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "vitiligo",
   "name": "Vitiligo",
   "part": "skin",
   "category": "autoimmune",
   "burden": 0.56,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "melasma",
   "name": "Melasma",
   "part": "skin",
   "category": "common",
   "burden": 0.56,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "pemphigus_vulgaris",
   "name": "Pemphigus vulgaris",
   "part": "skin",
   "category": "autoimmune",
   "burden": 0.56,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "keloid",
   "name": "Keloid",
   "part": "skin",
   "category": "common",
   "burden": 0.56,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "prickly_heat_miliaria",
   "name": "Prickly heat (miliaria)",
   "part": "skin",
   "category": "common",
   "burden": 0.56,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "acanthosis_nigricans",
   "name": "Acanthosis nigricans",
   "part": "skin",
   "category": "common",
   "burden": 0.56,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "mongolian_spot",
   "name": "Mongolian spot",
   "part": "skin",
   "category": "common",
   "burden": 0.56,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "dermatosis_papulosa_nigra",
   "name": "Dermatosis papulosa nigra",
   "part": "skin",
   "category": "common",
   "burden": 0.56,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "rheumatoid_arthritis",
   "name": "Rheumatoid arthritis",
   "part": "joints",
   "category": "autoimmune",
   "burden": 0.56,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "frozen_shoulder",
   "name": "Frozen shoulder",
   "part": "joints",
   "category": "common",
   "burden": 0.56,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "inguinal_hernia",
   "name": "Inguinal hernia",
   "part": "muscles",
   "category": "common",
   "burden": 0.56,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "neonatal_jaundice",
   "name": "Neonatal jaundice",
   "part": "blood",
   "category": "congenital",
   "burden": 0.56,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "allergic_rhinitis",
   "name": "Allergic rhinitis",
   "part": "immune",
   "category": "common",
   "burden": 0.56,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "epilepsy",
   "name": "Epilepsy",
   "part": "brain",
   "category": "neurological",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "depression",
   "name": "Depression",
   "part": "brain",
   "category": "mental",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "anxiety_disorder",
   "name": "Anxiety disorder",
   "part": "brain",
   "category": "mental",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "heat_stroke",
   "name": "Heat stroke",
   "part": "brain",
   "category": "environmental",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "alcohol_use_disorder",
   "name": "Alcohol use disorder",
   "part": "brain",
   "category": "mental",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "substance_use_disorder",
   "name": "Substance use disorder",
   "part": "brain",
   "category": "mental",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "diabetic_retinopathy",
   "name": "Diabetic retinopathy",
   "part": "eyes",
   "category": "complication",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "retinopathy_of_prematurity",
   "name": "Retinopathy of prematurity",
   "part": "eyes",
   "category": "paediatric",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "atrophic_rhinitis",
   "name": "Atrophic rhinitis",
   "part": "ears",
   "category": "chronic",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "oral_submucous_fibrosis",
   "name": "Oral submucous fibrosis",
   "part": "mouth",
   "category": "precancer",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "leukoplakia",
   "name": "Leukoplakia",
   "part": "mouth",
   "category": "precancer",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "dental_fluorosis",
   "name": "Dental fluorosis",
   "part": "mouth",
   "category": "environmental",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "epiglottitis",
   "name": "Epiglottitis",
   "part": "mouth",
   "category": "acute",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "hypothyroidism",
   "name": "Hypothyroidism",
   "part": "thyroid",
   "category": "endocrine",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "goitre",
   "name": "Goitre",
   "part": "thyroid",
   "category": "endocrine",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "hirsutism",
   "name": "Hirsutism",
   "part": "thyroid",
   "category": "endocrine",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "sheehan_s_syndrome",
   "name": "Sheehan's syndrome",
   "part": "thyroid",
   "category": "endocrine",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "diabetic_foot",
   "name": "Diabetic foot",
   "part": "thyroid",
   "category": "complication",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "heart_attack",
   "name": "Heart attack",
   "part": "heart",
   "category": "acute",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "mitral_stenosis",
   "name": "Mitral stenosis",
   "part": "heart",
   "category": "structural",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "tricuspid_stenosis",
   "name": "Tricuspid stenosis",
   "part": "heart",
   "category": "structural",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "lymphoedema",
   "name": "Lymphoedema",
   "part": "vessels",
   "category": "chronic",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "buerger_s_disease",
   "name": "Buerger's disease",
   "part": "vessels",
   "category": "chronic",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "asthma",
   "name": "Asthma",
   "part": "lungs",
   "category": "chronic",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "copd",
   "name": "COPD",
   "part": "lungs",
   "category": "chronic",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "silicosis",
   "name": "Silicosis",
   "part": "lungs",
   "category": "occupational",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "bronchiectasis",
   "name": "Bronchiectasis",
   "part": "lungs",
   "category": "chronic",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "pleural_effusion",
   "name": "Pleural effusion",
   "part": "lungs",
   "category": "acute",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "pneumoconiosis",
   "name": "Pneumoconiosis",
   "part": "lungs",
   "category": "occupational",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "byssinosis",
   "name": "Byssinosis",
   "part": "lungs",
   "category": "occupational",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "asbestosis",
   "name": "Asbestosis",
   "part": "lungs",
   "category": "occupational",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "coal_worker_s_pneumoconiosis",
   "name": "Coal worker's pneumoconiosis",
   "part": "lungs",
   "category": "occupational",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "cirrhosis",
   "name": "Cirrhosis",
   "part": "liver",
   "category": "chronic",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "alcoholic_liver_disease",
   "name": "Alcoholic liver disease",
   "part": "liver",
   "category": "chronic",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "cholestasis_of_pregnancy",
   "name": "Cholestasis of pregnancy",
   "part": "liver",
   "category": "maternal",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "ascending_cholangitis",
   "name": "Ascending cholangitis",
   "part": "liver",
   "category": "acute",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "spontaneous_bacterial_peritonitis",
   "name": "Spontaneous bacterial peritonitis",
   "part": "liver",
   "category": "complication",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "tropical_sprue",
   "name": "Tropical sprue",
   "part": "intestines",
   "category": "chronic",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "rectovaginal_fistula",
   "name": "Rectovaginal fistula",
   "part": "intestines",
   "category": "complication",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "environmental_enteropathy",
   "name": "Environmental enteropathy",
   "part": "intestines",
   "category": "chronic",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "chronic_pancreatitis",
   "name": "Chronic pancreatitis",
   "part": "pancreas",
   "category": "chronic",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "chronic_kidney_disease",
   "name": "Chronic kidney disease",
   "part": "kidneys",
   "category": "chronic",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "diabetic_nephropathy",
   "name": "Diabetic nephropathy",
   "part": "kidneys",
   "category": "complication",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "diabetic_kidney_disease",
   "name": "Diabetic kidney disease",
   "part": "kidneys",
   "category": "complication",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "renal_papillary_necrosis",
   "name": "Renal papillary necrosis",
   "part": "kidneys",
   "category": "complication",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "hypertensive_kidney_disease",
   "name": "Hypertensive kidney disease",
   "part": "kidneys",
   "category": "chronic",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "reflux_nephropathy",
   "name": "Reflux nephropathy",
   "part": "kidneys",
   "category": "chronic",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "analgesic_nephropathy",
   "name": "Analgesic nephropathy",
   "part": "kidneys",
   "category": "chronic",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "pyonephrosis",
   "name": "Pyonephrosis",
   "part": "kidneys",
   "category": "acute",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "nephrocalcinosis",
   "name": "Nephrocalcinosis",
   "part": "kidneys",
   "category": "chronic",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "vesicovaginal_fistula",
   "name": "Vesicovaginal fistula",
   "part": "bladder",
   "category": "complication",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "polycystic_ovary_syndrome",
   "name": "Polycystic ovary syndrome",
   "part": "repro_f",
   "category": "endocrine",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "pre_eclampsia",
   "name": "Pre-eclampsia",
   "part": "repro_f",
   "category": "maternal",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "ectopic_pregnancy",
   "name": "Ectopic pregnancy",
   "part": "repro_f",
   "category": "acute",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "postpartum_depression",
   "name": "Postpartum depression",
   "part": "repro_f",
   "category": "mental",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "eclampsia",
   "name": "Eclampsia",
   "part": "repro_f",
   "category": "maternal",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "obstetric_fistula",
   "name": "Obstetric fistula",
   "part": "repro_f",
   "category": "maternal",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "postpartum_haemorrhage",
   "name": "Postpartum haemorrhage",
   "part": "repro_f",
   "category": "maternal",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "cervical_dysplasia_cin",
   "name": "Cervical dysplasia (CIN)",
   "part": "repro_f",
   "category": "precancer",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "placental_abruption",
   "name": "Placental abruption",
   "part": "repro_f",
   "category": "maternal",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "hellp_syndrome",
   "name": "HELLP syndrome",
   "part": "repro_f",
   "category": "maternal",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "chorioamnionitis",
   "name": "Chorioamnionitis",
   "part": "repro_f",
   "category": "maternal",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "stillbirth",
   "name": "Stillbirth",
   "part": "repro_f",
   "category": "maternal",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "placenta_accreta",
   "name": "Placenta accreta",
   "part": "repro_f",
   "category": "maternal",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "oligohydramnios",
   "name": "Oligohydramnios",
   "part": "repro_f",
   "category": "maternal",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "fournier_s_gangrene",
   "name": "Fournier's gangrene",
   "part": "repro_m",
   "category": "acute",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "arsenicosis_skin",
   "name": "Arsenicosis (skin)",
   "part": "skin",
   "category": "environmental",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "stevens_johnson_syndrome",
   "name": "Stevens–Johnson syndrome",
   "part": "skin",
   "category": "acute",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "skeletal_fluorosis",
   "name": "Skeletal fluorosis",
   "part": "bones",
   "category": "environmental",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "renal_osteodystrophy",
   "name": "Renal osteodystrophy",
   "part": "bones",
   "category": "complication",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "neuropathic_arthropathy_charcot_joint",
   "name": "Neuropathic arthropathy (Charcot joint)",
   "part": "joints",
   "category": "complication",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "sepsis",
   "name": "Sepsis",
   "part": "immune",
   "category": "acute",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "snakebite_envenomation",
   "name": "Snakebite envenomation",
   "part": "immune",
   "category": "environmental",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  },
  {
   "id": "kikuchi_disease",
   "name": "Kikuchi disease",
   "part": "immune",
   "category": "rare",
   "burden": 0.552,
   "gap": "High India burden, but no verified India incidence figure exists yet and no genomic handle in our data - a measurement gap, not yet a study."
  }
 ]
}